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TCPTP (PTPN2) Human Gene Knockout Kit (CRISPR)

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SKU
KN202161BN
PTPN2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "TCPTP or NM_001207013"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol TCPTP
Locus ID 5771
Components

KN202161G1, TCPTP gRNA vector 1 in pCas-Guide CRISPR vector

KN202161G2, TCPTP gRNA vector 2 in pCas-Guide CRISPR vector

KN202161BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001207013, NM_001308287, NM_002828, NM_080422, NM_080423
UniProt ID P17706
Synonyms PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. provided by RefSeq, May 2011
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Other Versions
SKU Description Size Price
GA103920 PTPN2 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase non-receptor type 2 1 kit
$1,657.00
KN202161 PTPN2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202161LP PTPN2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202161RB PTPN2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402161 PTPN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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