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PKM2 (PKM) Human Gene Knockout Kit (CRISPR)

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SKU
KN201855BN
PKM - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PKM2 or NM_001206796"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PKM2
Locus ID 5315
Components

KN201855G1, PKM2 gRNA vector 1 in pCas-Guide CRISPR vector

KN201855G2, PKM2 gRNA vector 2 in pCas-Guide CRISPR vector

KN201855BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001206796, NM_001206797, NM_001206798, NM_001206799, NM_001316318, NM_002654, NM_182470, NM_182471
UniProt ID P14618
Synonyms CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1
Summary This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. provided by RefSeq, May 2011
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Documents
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Other Versions
SKU Description Size Price
GA103576 PKM CRISPRa kit - CRISPR gene activation of human pyruvate kinase M1/2 1 kit
$1,657.00
KN201855 PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201855LP PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201855RB PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401855 PKM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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