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Human PKM2 (PKM) activation kit by CRISPRa

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SKU
GA103576
PKM CRISPRa kit - CRISPR gene activation of human pyruvate kinase M1/2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "PKM"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PKM
Locus ID 5315
Components

GA103576G1, PKM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103576G2, PKM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103576G3, PKM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001206796, NM_001206797, NM_001206798, NM_001206799, NM_001316318, NM_002654, NM_182470, NM_182471
UniProt ID P14618
Synonyms CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1
Summary This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. provided by RefSeq, May 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN201855 PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201855BN PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201855LP PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201855RB PKM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401855 PKM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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