TCTP (TPT1) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | TCTP |
| Locus ID | 7178 |
| Components |
KN201664G1, TCTP gRNA vector 1 in pCas-Guide CRISPR vector KN201664G2, TCTP gRNA vector 2 in pCas-Guide CRISPR vector KN201664LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001286272, NM_001286273, NM_003295 |
| UniProt ID | P13693 |
| Synonyms | HRF; p02; p23; TCTP |
| Summary | This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Aug 2017 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA104961 | TPT1 CRISPRa kit - CRISPR gene activation of human tumor protein, translationally-controlled 1 | 1 kit |
$1,657.00
|
|
| KN201664 | TPT1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201664BN | TPT1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201664RB | TPT1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN401664 | TPT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.