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EBP50 (SLC9A3R1) Human Gene Knockout Kit (CRISPR)

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SKU
KN201653BN
SLC9A3R1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "EBP50 or NM_004252"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol EBP50
Locus ID 9368
Components

KN201653G1, EBP50 gRNA vector 1 in pCas-Guide CRISPR vector

KN201653G2, EBP50 gRNA vector 2 in pCas-Guide CRISPR vector

KN201653BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004252
UniProt ID O14745
Synonyms EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Summary This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.provided by RefSeq, Sep 2009
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Documents
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Other Versions
SKU Description Size Price
GA106248 SLC9A3R1 CRISPRa kit - CRISPR gene activation of human SLC9A3 regulator 1 1 kit
$1,657.00
KN201653 SLC9A3R1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201653LP SLC9A3R1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201653RB SLC9A3R1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401653 SLC9A3R1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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