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DR5 (TNFRSF10B) Human Gene Knockout Kit (CRISPR)

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SKU
KN201588RB
TNFRSF10B - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "DR5 or NM_003842"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol DR5
Locus ID 8795
Components

KN201588G1, DR5 gRNA vector 1 in pCas-Guide CRISPR vector

KN201588G2, DR5 gRNA vector 2 in pCas-Guide CRISPR vector

KN201588RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003842, NM_147187, NR_027140
UniProt ID O14763
Synonyms CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. provided by RefSeq, Mar 2009
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Other Versions
SKU Description Size Price
GA105841 TNFRSF10B CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 10b 1 kit
$1,657.00
KN201588 TNFRSF10B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201588BN TNFRSF10B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201588LP TNFRSF10B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401588 TNFRSF10B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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