PPAR gamma (PPARG) Human Gene Knockout Kit (CRISPR)

SKU
KN201538BN
PPARG - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PPAR gamma
Locus ID 5468
Components

KN201538G1, PPAR gamma gRNA vector 1 in pCas-Guide CRISPR vector

KN201538G2, PPAR gamma gRNA vector 2 in pCas-Guide CRISPR vector

KN201538BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001330615, NM_005037, NM_015869, NM_138711, NM_138712, NM_001354666, NM_001354667, NM_001354668, NM_001354669, NM_001354670
UniProt ID P37231
Synonyms CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA103688 PPARG CRISPRa kit - CRISPR gene activation of human peroxisome proliferator activated receptor gamma 1 kit
$1,657.00
KN201538 PPARG - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201538LP PPARG - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201538RB PPARG - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401538 PPARG - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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