NFIL3 Human Gene Knockout Kit (CRISPR)

SKU KN201537RB

NFIL3 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Vector: RFP-BSD
• Target Symbol: NFIL3
• Locus ID: 4783
• Components:

  KN201537G1, NFIL3 gRNA vector 1 in pCas-Guide CRISPR vector

  KN201537G2, NFIL3 gRNA vector 2 in pCas-Guide CRISPR vector

  KN201537RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001289999, NM_001290000, NM_005384
• UniProt ID: Q16649
• Synonyms: E4BP4; IL3BP1; NF-IL3A; NFIL3A
• Summary: The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
• Shipping: Ambient