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RIOK2 Human Gene Knockout Kit (CRISPR)

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SKU
KN201484LP
RIOK2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA505140 RIOK2 mouse monoclonal antibody, clone OTI3E11 (formerly 3E11) 100 ul
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RC201484 RIOK2 (Myc-DDK-tagged)-Human RIO kinase 2 (RIOK2), transcript variant 1
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "RIOK2 or NM_001159749"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol RIOK2
Locus ID 55781
Components

KN201484G1, RIOK2 gRNA vector 1 in pCas-Guide CRISPR vector

KN201484G2, RIOK2 gRNA vector 2 in pCas-Guide CRISPR vector

KN201484LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001159749, NM_018343
UniProt ID Q9BVS4
Synonyms RIO2
Summary Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA110964 RIOK2 CRISPRa kit - CRISPR gene activation of human RIO kinase 2 1 kit
$1,657.00
KN201484 RIOK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201484BN RIOK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201484RB RIOK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401484 RIOK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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