RAB10 Human Gene Knockout Kit (CRISPR)

SKU KN201464RB

RAB10 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Vector: RFP-BSD
• Target Symbol: RAB10
• Locus ID: 10890
• Components:

  KN201464G1, RAB10 gRNA vector 1 in pCas-Guide CRISPR vector

  KN201464G2, RAB10 gRNA vector 2 in pCas-Guide CRISPR vector

  KN201464RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_016131
• UniProt ID: P61026
• Synonyms: Ac1075; RAB10, member RAS oncogene family; ras-related protein rab10
• Summary: RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]
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