CAP1 Human Gene Knockout Kit (CRISPR)

CAT#: KN201394BN

CAP1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: CAP1
• Locus ID: 10487
• Components:

  KN201394G1, CAP1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN201394G2, CAP1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN201394BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001105530, NM_001330502, NM_006367, NM_001350475, NM_001350476, NM_001350477, NM_001350478, NM_001350479, NM_001350480, NM_001350481, NM_001350482, NM_001350483, NM_001350484, NM_001350485
• UniProt ID: Q01518
• Synonyms: CAP; CAP1-PEN
• Summary: The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016]