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MYH (MUTYH) Human Gene Knockout Kit (CRISPR)

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SKU
KN201376LP
MUTYH - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "MYH or NM_001048171"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol MYH
Locus ID 4595
Components

KN201376G1, MYH gRNA vector 1 in pCas-Guide CRISPR vector

KN201376G2, MYH gRNA vector 2 in pCas-Guide CRISPR vector

KN201376LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001048171, NM_001048172, NM_001048173, NM_001048174, NM_001128425, NM_001293190, NM_001293191, NM_001293192, NM_001293195, NM_001293196, NM_012222, NM_001350650, NM_001350651, NR_146882, NR_146883
UniProt ID Q9UIF7
Synonyms MYH
Summary This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2017
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Documents
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Other Versions
SKU Description Size Price
GA103042 MUTYH CRISPRa kit - CRISPR gene activation of human mutY DNA glycosylase 1 kit
$1,657.00
KN201376 MUTYH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201376BN MUTYH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201376RB MUTYH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401376 MUTYH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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