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APPBP1 (NAE1) Human Gene Knockout Kit (CRISPR)

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SKU
KN201326LP
NAE1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "APPBP1 or NM_001018159"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol APPBP1
Locus ID 8883
Components

KN201326G1, APPBP1 gRNA vector 1 in pCas-Guide CRISPR vector

KN201326G2, APPBP1 gRNA vector 2 in pCas-Guide CRISPR vector

KN201326LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001018159, NM_001018160, NM_001286500, NM_003905
UniProt ID Q13564
Synonyms A-116A10.1; APPBP1; HPP1; ula-1
Summary The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA105916 NAE1 CRISPRa kit - CRISPR gene activation of human NEDD8 activating enzyme E1 subunit 1 1 kit
$1,657.00
KN201326 NAE1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201326BN NAE1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201326RB NAE1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401326 NAE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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