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MCK10 (DDR1) Human Gene Knockout Kit (CRISPR)

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SKU
KN201224LP
DDR1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "MCK10 or NM_001202521"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol MCK10
Locus ID 780
Components

KN201224G1, MCK10 gRNA vector 1 in pCas-Guide CRISPR vector

KN201224G2, MCK10 gRNA vector 2 in pCas-Guide CRISPR vector

KN201224LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001202521, NM_001202522, NM_001202523, NM_001297652, NM_001297653, NM_001297654, NM_001954, NM_013993, NM_013994
UniProt ID Q08345
Synonyms CAK; CD167; DDR; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE
Summary Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Feb 2011
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Documents
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Other Versions
SKU Description Size Price
GA100545 DDR1 CRISPRa kit - CRISPR gene activation of human discoidin domain receptor tyrosine kinase 1 1 kit
$1,657.00
KN201224 DDR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201224BN DDR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201224RB DDR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401224 DDR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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