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Sigma1 receptor (SIGMAR1) Human Gene Knockout Kit (CRISPR)

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SKU
KN201206LP
SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Sigma1 receptor or NM_001282205"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Sigma1 receptor
Locus ID 10280
Components

KN201206G1, Sigma1 receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN201206G2, Sigma1 receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN201206LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001282205, NM_001282206, NM_001282207, NM_001282208, NM_001282209, NM_005866, NM_147157, NM_147158, NM_147159, NM_147160, NR_104108
UniProt ID Q99720
Synonyms ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP
Summary This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. provided by RefSeq, Aug 2013
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Resources
Other Versions
SKU Description Size Price
GA107002 SIGMAR1 CRISPRa kit - CRISPR gene activation of human sigma non-opioid intracellular receptor 1 1 kit
$1,657.00
KN201206 SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201206BN SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201206RB SIGMAR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401206 SIGMAR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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