Mucolipin 1 (MCOLN1) Human Gene Knockout Kit (CRISPR)

SKU
KN201010LP
MCOLN1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Mucolipin 1
Locus ID 57192
Components

KN201010G1, Mucolipin 1 gRNA vector 1 in pCas-Guide CRISPR vector

KN201010G2, Mucolipin 1 gRNA vector 2 in pCas-Guide CRISPR vector

KN201010LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_020533
UniProt ID Q9GZU1
Synonyms MG-2; ML4; MLIV; MST080; MSTP080; TRP-ML1; TRPM-L1; TRPML1
Summary This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. provided by RefSeq, Oct 2009
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Other Versions
SKU Description Size Price
GA111441 MCOLN1 CRISPRa kit - CRISPR gene activation of human mucolipin 1 1 kit
$1,657.00
KN201010 MCOLN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201010BN MCOLN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201010RB MCOLN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401010 MCOLN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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