MSI2 Human Gene Knockout Kit (CRISPR)

SKU KN201003LP

MSI2 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: MSI2
• Locus ID: 124540
• Components:

  KN201003G1, MSI2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN201003G2, MSI2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN201003LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001322250, NM_001322251, NM_138962, NM_170721
• UniProt ID: Q96DH6
• Synonyms: MSI2H
• Summary: This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
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