HTF9C (TRMT2A) Human Gene Knockout Kit (CRISPR)

CAT#: KN200966BN

TRMT2A - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: HTF9C
• Locus ID: 27037
• Components:

  KN200966G1, HTF9C gRNA vector 1 in pCas-Guide CRISPR vector

  KN200966G2, HTF9C gRNA vector 2 in pCas-Guide CRISPR vector

  KN200966BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001257994, NM_001331039, NM_022727, NM_182984
• UniProt ID: Q8IZ69
• Synonyms: HTF9C
• Summary: The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]