ICAM1 Human Gene Knockout Kit (CRISPR)

CAT#: KN200714RB

ICAM1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: ICAM1
• Locus ID: 3383
• Components:

  KN200714G1, ICAM1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN200714G2, ICAM1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN200714RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_000201
• UniProt ID: P05362
• Synonyms: BB2; CD54; P3.58
• Summary: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]