HNRNPD Human Gene Knockout Kit (CRISPR)

SKU
KN200660LP
HNRNPD - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol HNRNPD
Locus ID 3184
Components

KN200660G1, HNRNPD gRNA vector 1 in pCas-Guide CRISPR vector

KN200660G2, HNRNPD gRNA vector 2 in pCas-Guide CRISPR vector

KN200660LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001003810, NM_002138, NM_031369, NM_031370
UniProt ID Q14103
Synonyms AUF1; AUF1A; hnRNPD0; HNRPD; P37
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. provided by RefSeq, Jul 2008
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Other Versions
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GA102173 HNRNPD CRISPRa kit - CRISPR gene activation of human heterogeneous nuclear ribonucleoprotein D 1 kit
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KN200660 HNRNPD - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN200660BN HNRNPD - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN200660RB HNRNPD - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400660 HNRNPD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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