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PRSS8 Human Gene Knockout Kit (CRISPR)

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SKU
KN200646LP
PRSS8 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "PRSS8 or NM_002773"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol PRSS8
Locus ID 5652
Components

KN200646G1, PRSS8 gRNA vector 1 in pCas-Guide CRISPR vector

KN200646G2, PRSS8 gRNA vector 2 in pCas-Guide CRISPR vector

KN200646LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002773
UniProt ID Q16651
Synonyms CAP1; PROSTASIN
Summary This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. provided by RefSeq, Feb 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA103831 PRSS8 CRISPRa kit - CRISPR gene activation of human serine protease 8 1 kit
$1,657.00
KN200646 PRSS8 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200646BN PRSS8 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200646RB PRSS8 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400646 PRSS8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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