NME6 Human Gene Knockout Kit (CRISPR)

CAT#: KN200541

NME6 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
• Donor DNA: GFP-puro
• Symbol: NME6
• Locus ID: 10201
• Components:

  KN200541G1, NME6 gRNA vector 1 in pCas-Guide CRISPR vector

  KN200541G2, NME6 gRNA vector 2 in pCas-Guide CRISPR vector

  KN200541D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001308426, NM_001308427, NM_001308428, NM_001308430, NM_001308431, NM_001308433, NM_001308434, NM_001308435, NM_005793
• UniProt ID: O75414
• Synonyms: IPIA-ALPHA; NDK 6; NM23-H6
• Summary: Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010]