GSK3 beta (GSK3B) Human Gene Knockout Kit (CRISPR)

SKU
KN200468LP
GSK3B - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol GSK3 beta
Locus ID 2932
Components

KN200468G1, GSK3 beta gRNA vector 1 in pCas-Guide CRISPR vector

KN200468G2, GSK3 beta gRNA vector 2 in pCas-Guide CRISPR vector

KN200468LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001146156, NM_002093, NM_001354596
UniProt ID P49841
Synonyms glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform
Summary The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. provided by RefSeq, Aug 2017
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Other Versions
SKU Description Size Price
GA101983 GSK3B CRISPRa kit - CRISPR gene activation of human glycogen synthase kinase 3 beta 1 kit
$1,657.00
KN200468 GSK3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200468BN GSK3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200468RB GSK3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400468 GSK3B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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