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CX3CL1 Human Gene Knockout Kit (CRISPR)

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SKU
KN200420RB
CX3CL1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CX3CL1 or NM_001304392"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol CX3CL1
Locus ID 6376
Components

KN200420G1, CX3CL1 gRNA vector 1 in pCas-Guide CRISPR vector

KN200420G2, CX3CL1 gRNA vector 2 in pCas-Guide CRISPR vector

KN200420RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001304392, NM_002996
UniProt ID P78423
Synonyms ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1
Summary This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. provided by RefSeq, Sep 2017
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Other Versions
SKU Description Size Price
GA104337 CX3CL1 CRISPRa kit - CRISPR gene activation of human C-X3-C motif chemokine ligand 1 1 kit
$1,657.00
KN200420 CX3CL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200420BN CX3CL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200420LP CX3CL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400420 CX3CL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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