Neuraminidase (NEU1) Human Gene Knockout Kit (CRISPR)

SKU
KN200386RB
NEU1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Neuraminidase
Locus ID 4758
Components

KN200386G1, Neuraminidase gRNA vector 1 in pCas-Guide CRISPR vector

KN200386G2, Neuraminidase gRNA vector 2 in pCas-Guide CRISPR vector

KN200386RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000434
UniProt ID Q99519
Synonyms NANH; NEU; SIAL1
Summary The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA103173 NEU1 CRISPRa kit - CRISPR gene activation of human neuraminidase 1 1 kit
$1,657.00
KN200386 NEU1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200386BN NEU1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200386LP NEU1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400386 NEU1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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