Mouse Plb1 activation kit by CRISPRa

SKU GA218325

Plb1 CRISPRa kit - CRISPR gene activation of mouse phospholipase B1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Plb1
• Locus ID: 665270
• Components:

  GA218325G1, Plb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA218325G2, Plb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA218325G3, Plb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001081407, NM_030072, NM_172147
• UniProt ID: Q3TTY0
• Synonyms: 4632413E21Rik; 4930433E17Rik; 4930539A06Rik; BC033606
• Summary: Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity).[UniProtKB/Swiss-Prot Function]