Mouse Angptl8 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Angptl8 |
| Locus ID | 624219 |
| Components |
GA218016G1, Angptl8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA218016G2, Angptl8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA218016G3, Angptl8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001080940 |
| UniProt ID | Q8R1L8 |
| Synonyms | EG624219; Gm6484; Rifl |
| Summary | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN506963 | Gm6484 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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