Mouse Primpol activation kit by CRISPRa

SKU
GA217442
Primpol CRISPRa kit - CRISPR gene activation of mouse primase and polymerase (DNA-directed)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Primpol
Locus ID 408022
Components

GA217442G1, Primpol gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA217442G2, Primpol gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA217442G3, Primpol gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001001184, NR_151680
UniProt ID Q6P1E7
Synonyms BC065112; Ccdc111
Summary DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN313866 Primpol - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN313866BN Primpol - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313866LP Primpol - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313866RB Primpol - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN513866 Primpol - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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