Mouse Rrm2b activation kit by CRISPRa

SKU
GA217266
Rrm2b CRISPRa kit - CRISPR gene activation of mouse ribonucleotide reductase M2 B (TP53 inducible)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Rrm2b
Locus ID 382985
Components

GA217266G1, Rrm2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA217266G2, Rrm2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA217266G3, Rrm2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_199476, NM_001357022, NM_001357023
UniProt ID Q6PEE3
Synonyms p53R2
Summary Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN515140 Rrm2b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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