Mouse Zcwpw1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Zcwpw1 |
| Locus ID | 381678 |
| Components |
GA217154G1, Zcwpw1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217154G2, Zcwpw1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217154G3, Zcwpw1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001005426, NM_001360023 |
| UniProt ID | Q6IR42 |
| Synonyms | Gm1053 |
| Summary | Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3) that facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs) (PubMed:32374261, PubMed:32352380, PubMed:32744506). Essential for male fertility and spermatogenesis (PubMed:31453335, PubMed:32374261, PubMed:32352380, PubMed:32744506). Required for meiosis prophase I progression in male but not in female germ cells (PubMed:31453335).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN519672 | Zcwpw1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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