Mouse Atp2b4 activation kit by CRISPRa

SKU GA217095

Atp2b4 CRISPRa kit - CRISPR gene activation of mouse ATPase, Ca++ transporting, plasma membrane 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Atp2b4
• Locus ID: 381290
• Components:

  GA217095G1, Atp2b4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA217095G2, Atp2b4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA217095G3, Atp2b4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001167949, NM_213616
• UniProt ID: Q6Q477
• Synonyms: Pmca4
• Summary: Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity). By regulating sperm cell calcium homeostasis, may play a role in sperm motility (PubMed:15078889).[UniProtKB/Swiss-Prot Function]