Mouse Abca17 activation kit by CRISPRa

SKU GA217068

Abca17 CRISPRa kit - CRISPR gene activation of mouse ATP-binding cassette, sub-family A (ABC1), member 17

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Abca17
• Locus ID: 381072
• Components:

  GA217068G1, Abca17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA217068G2, Abca17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA217068G3, Abca17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001031621
• UniProt ID: E9PX95
• Summary: Promotes cholesterol efflux from sperm which renders sperm capable of fertilization (PubMed:22237709). Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols (PubMed:15810880).[UniProtKB/Swiss-Prot Function]