Mouse Mks1 activation kit by CRISPRa

SKU GA217024

Mks1 CRISPRa kit - CRISPR gene activation of mouse Meckel syndrome, type 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mks1
• Locus ID: 380718
• Components:

  GA217024G1, Mks1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA217024G2, Mks1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA217024G3, Mks1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001039684
• UniProt ID: Q5SW45
• Synonyms: AK190930; B8d3
• Summary: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.[UniProtKB/Swiss-Prot Function]