Mouse Bpi activation kit by CRISPRa

SKU GA216749

Bpi CRISPRa kit - CRISPR gene activation of mouse bactericidal permeablility increasing protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Bpi
• Locus ID: 329547
• Components:

  GA216749G1, Bpi gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA216749G2, Bpi gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA216749G3, Bpi gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_177850, NM_001356542
• UniProt ID: Q67E05
• Synonyms: 9230105K17Rik; Bpifd1
• Summary: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.[UniProtKB/Swiss-Prot Function]