Mouse Serpinb1b activation kit by CRISPRa

SKU
GA216198
Serpinb1b CRISPRa kit - CRISPR gene activation of mouse serine (or cysteine) peptidase inhibitor, clade B, member 1b
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Serpinb1b
Locus ID 282663
Components

GA216198G1, Serpinb1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA216198G2, Serpinb1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA216198G3, Serpinb1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_173052
UniProt ID Q8VHP7
Synonyms 6330533H24Rik; EIB; ovalbumin; Serpin1b1
Summary Regulates the activity of the neutrophil proteases. Forms only a stable complex with CTSG/Cathepsin G (PubMed:12189154). During inflammation, limits the activity of inflammatory caspases CASP1 and CASP4 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation (PubMed:30692621).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN515580 Serpinb1b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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