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Mouse Spib activation kit by CRISPRa

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SKU
GA216128
Spib CRISPRa kit - CRISPR gene activation of mouse Spi-B transcription factor (Spi-1/PU.1 related)
  $1,657.00
4 Weeks*

Other products for "Spib"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Spib
Locus ID 272382
Components

GA216128G1, Spib gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA216128G2, Spib gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA216128G3, Spib gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_019866
UniProt ID O35906
Synonyms Spi-B
Summary Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. Required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN516603 Spib - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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