Mouse Nrip1 activation kit by CRISPRa

SKU GA215964

Nrip1 CRISPRa kit - CRISPR gene activation of mouse nuclear receptor interacting protein 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Nrip1
• Locus ID: 268903
• Components:

  GA215964G1, Nrip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215964G2, Nrip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215964G3, Nrip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173440, NM_001358238
• UniProt ID: Q8CBD1
• Synonyms: 6030458L20Rik; 8430438I05Rik; 9630050P12; AA959574; AW456757; RIP140
• Summary: Modulates transcriptional repression by nuclear hormone receptors such as NR2C1, thyroid hormone receptor and retinoic acid receptor/RARA. Essential for cumulus expansion and follicle rupture during ovulation. Also controls the balance between fat accumulation and energy expenditure. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC.[UniProtKB/Swiss-Prot Function]