Mouse Neto1 activation kit by CRISPRa

SKU GA215343

Neto1 CRISPRa kit - CRISPR gene activation of mouse neuropilin (NRP) and tolloid (TLL)-like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Neto1
• Locus ID: 246317
• Components:

  GA215343G1, Neto1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215343G2, Neto1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215343G3, Neto1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_144946, NM_001360910
• UniProt ID: Q8R4I7
• Synonyms: AI851453; Btcl1; C130005O10Rik
• Summary: Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.[UniProtKB/Swiss-Prot Function]