Mouse Klf8 activation kit by CRISPRa

SKU GA215296

Klf8 CRISPRa kit - CRISPR gene activation of mouse Kruppel-like factor 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Klf8
• Locus ID: 245671
• Components:

  GA215296G1, Klf8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215296G2, Klf8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215296G3, Klf8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173780, NM_001357183
• UniProt ID: Q8BLM0
• Synonyms: A830097P10Rik; BKLF3; ZNF74
• Summary: Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK) (By similarity).[UniProtKB/Swiss-Prot Function]