Mouse Fbxl5 activation kit by CRISPRa

SKU
GA215095
Fbxl5 CRISPRa kit - CRISPR gene activation of mouse F-box and leucine-rich repeat protein 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fbxl5
Locus ID 242960
Components

GA215095G1, Fbxl5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA215095G2, Fbxl5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA215095G3, Fbxl5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001159963, NM_178729
UniProt ID Q8C2S5
Synonyms Fbl4; Fir4
Summary Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN505799 Fbxl5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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