Mouse Adamts12 activation kit by CRISPRa

SKU
GA214845
Adamts12 CRISPRa kit - CRISPR gene activation of mouse a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Adamts12
Locus ID 239337
Components

GA214845G1, Adamts12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214845G2, Adamts12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214845G3, Adamts12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_175501
UniProt ID Q811B3
Synonyms ADAMTS-12; AI605170
Summary This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active protease. Mice lacking the encoded protein exhibit increased angiogenic response and tumor invasion in different models of angiogenesis and, severe inflammation and delayed recovery when subjected to experimental conditions that induce colitis, endotoxic sepsis and pancreatitis. provided by RefSeq, Jul 2016
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Other Versions
SKU Description Size Price
KN500850 Adamts12 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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