Mouse Pfas activation kit by CRISPRa

SKU GA214748

Pfas CRISPRa kit - CRISPR gene activation of mouse phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Pfas
• Locus ID: 237823
• Components:

  GA214748G1, Pfas gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA214748G2, Pfas gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA214748G3, Pfas gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001159519
• UniProt ID: Q5SUR0
• Synonyms: 4432409B16Rik; FGAMS; FGAR-AT; FGARAT; Gm18; PURL; Sofa
• Summary: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity).[UniProtKB/Swiss-Prot Function]