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Mouse Gpr75 activation kit by CRISPRa

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SKU
GA214740
Gpr75 CRISPRa kit - CRISPR gene activation of mouse G protein-coupled receptor 75
  $1,657.00
4 Weeks*

Other products for "Gpr75"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Gpr75
Locus ID 237716
Components

GA214740G1, Gpr75 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214740G2, Gpr75 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214740G3, Gpr75 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_175490
UniProt ID Q6X632
Summary G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN507259 Gpr75 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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