Mouse Nox1 activation kit by CRISPRa

SKU GA214700

Nox1 CRISPRa kit - CRISPR gene activation of mouse NADPH oxidase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Nox1
• Locus ID: 237038
• Components:

  GA214700G1, Nox1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA214700G2, Nox1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA214700G3, Nox1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_172203
• UniProt ID: Q8CIZ9
• Synonyms: GP91-2; MOX1; NOH-1; NOH1; Nox-1; NOX1a; NOX1alpha
• Summary: This gene encodes a subunit of the NADPH oxidase enzyme, which is a membrane-bound, multisubunit protein. This complex catalyzes the transfer of electrons from NADPH to molecular oxygen to produce superoxide or hydrogen peroxide and may have a role in antimicrobial killing and cell signaling. This protein binds other subunits in order to produce superoxide. In mouse, deficiency of this enzyme may be associated with changes in blood pressure. [provided by RefSeq, Jun 2013]