Mouse Lingo1 activation kit by CRISPRa

SKU
GA214621
Lingo1 CRISPRa kit - CRISPR gene activation of mouse leucine rich repeat and Ig domain containing 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Lingo1
Locus ID 235402
Components

GA214621G1, Lingo1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214621G2, Lingo1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214621G3, Lingo1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001311076, NM_181074, NM_001361115, NM_001361116, NM_001361117, NM_001361118, NM_001361119, NM_001361120
UniProt ID Q9D1T0
Synonyms 4930471K13Rik; AV148400; LERN1; LINGO-1; Lrrn6a; UNQ201
Summary Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN509305 Lingo1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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