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Mouse Tmem119 activation kit by CRISPRa

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SKU
GA214275
Tmem119 CRISPRa kit - CRISPR gene activation of mouse transmembrane protein 119
  $1,657.00
4 Weeks*

Other products for "Tmem119"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tmem119
Locus ID 231633
Components

GA214275G1, Tmem119 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214275G2, Tmem119 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214275G3, Tmem119 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_146162
UniProt ID Q8R138
Synonyms AW208946; BC025600; obif
Summary Plays an important role in bone formation and normal bone mineralization (PubMed:26207632, PubMed:22416756, PubMed:20025746). Promotes the differentiation of myoblasts into osteoblasts (PubMed:22416756, PubMed:20025746, PubMed:22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed:21239498, PubMed:22579779). Upregulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed:26207632).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN517704 Tmem119 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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