Mouse Lin54 activation kit by CRISPRa

SKU
GA214261
Lin54 CRISPRa kit - CRISPR gene activation of mouse lin-54 homolog (C. elegans)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Lin54
Locus ID 231506
Components

GA214261G1, Lin54 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214261G2, Lin54 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214261G3, Lin54 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001115010, NM_001346583, NM_172714, NM_001359914
UniProt ID Q571G4
Synonyms AI461788
Summary Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN509300 Lin54 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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