Mouse Gckr activation kit by CRISPRa

SKU
GA214239
Gckr CRISPRa kit - CRISPR gene activation of mouse glucokinase regulatory protein
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Gckr
Locus ID 231103
Components

GA214239G1, Gckr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214239G2, Gckr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214239G3, Gckr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_144909
UniProt ID Q91X44
Synonyms GKRP
Summary Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN506365 Gckr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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