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Mouse Smg5 activation kit by CRISPRa

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SKU
GA214077
Smg5 CRISPRa kit - CRISPR gene activation of mouse Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
  $1,657.00
4 Weeks*

Other products for "Smg5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Smg5
Locus ID 229512
Components

GA214077G1, Smg5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214077G2, Smg5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214077G3, Smg5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_178246, NM_173188
UniProt ID Q6ZPY2
Synonyms BC024683; mKIAA1089
Summary Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN516311 Smg5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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