Mouse Kmt5b activation kit by CRISPRa

SKU
GA213803
Kmt5b CRISPRa kit - CRISPR gene activation of mouse lysine methyltransferase 5B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Kmt5b
Locus ID 225888
Components

GA213803G1, Kmt5b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213803G2, Kmt5b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213803G3, Kmt5b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001167884, NM_001167885, NM_001167886, NM_001167887, NM_001167888, NM_001167889, NM_144871
UniProt ID Q3U8K7
Synonyms AA117471; C630029K18Rik; Suv4-20h1; Suv420h1
Summary Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN517007 Suv420h1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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